Gene name:
TNFRSF10D(UNQ251/PRO288;DCR2;TRAILR4;TRUNDD);
Protein name:
Tumor necrosis factor receptor superfamily member 10D;
Alternative:
TNF-related apoptosis-inducing ligand receptor 4(TRAIL receptor 4;TRAIL-R4);Decoy receptor 2(DcR2);TRAIL receptor with a truncated death domain;
CD:
CD264;
Organism:
Human (Homo sapiens).
General Annotation
Function:
Receptor for the cytotoxic ligand TRAIL. Contains a truncated death domain and hence is not capable of inducing apoptosis but protects against TRAIL-mediated apoptosis. Reports are contradictory with regards to its ability to induce the NF-kappa-B pathway. According to PubMed:9382840, it cannot but according to PubMed:9430226, it can induce the NF-kappa-B pathway.
Subcellular Location:
Membrane
Single-pass type I membrane protein
Protein Attributes:
50:
MGLWGQSVPT | ASSARAGRYP | GARTASGTRP | WLLDPKILKF | VVFIVAVLLP |
100:
VRVDSATIPR | QDEVPQQTVA | PQQQRRSLKE | EECPAGSHRS | EYTGACNPCT |
150:
EGVDYTIASN | NLPSCLLCTV | CKSGQTNKSS | CTTTRDTVCQ | CEKGSFQDKN |
200:
SPEMCRTCRT | GCPRGMVKVS | NCTPRSDIKC | KNESAASSTG | KTPAAEETVT |
250:
TILGMLASPY | HYLIIIVVLV | IILAVVVVGF | SCRKKFISYL | KGICSGGGGG |
300:
PERVHRVLFR | RRSCPSRVPG | AEDNARNETL | SNRYLQPTQV | SEQEIQGQEL |
350:
AELTGVTVES | PEEPQRLLEQ | AEAEGCQRRR | LLVPVNDADS | ADISTLLDAS |
386:
ATLEEGHAKE | TIQDQLVGSE | KLFYEEDEAG | SATSCL
Vaild Sequence:
Related Databases
Uniprot:
